A hero in the Earth-Minbari-War, Sheridan served on the warship Agamemnon where he became known to the Minbari as "Star Killer" after faking a distress signal.

His wife, Anna, served on an explorer class ship, The Icarus, and was presumed dead after encountering the planet known as Z'Ha'Dum. Years later, Anna reappeared after being brainwashed by the Shadows, but later died at the hands of Sheridan on the very planet that "saved" her.

Sheridan took command of Babylon 5 following Jeffrey Sinclair's departure. When President Clark ordered him to stand down, he instead had Babylon 5 secede from the Earth Alliance.

He is romantically involved with Ambassador Delenn and in one possible future they have a son named David. Now president of the new Interstellar Alliance and commander of the Forces of Light, Sheridan's voice is heard by millions who both respect him and fear him.